The global emergence of multidrug-resistant (MDR) Klebsiella pneumoniae, particularly carbapenem-resistant K.pneumoniae (CRKP), presents a severe public health threat, limiting available treatment options.Tigecycline and eravacycline, have been considered a last-resort therapeutic against MDR Enterobacteriaceae.However, strains were resistant to th
Implementation of an infrastructure to support digital pathology began in 2006 at Memorial Sloan Kettering Cancer Center.The public health emergency and COVID-19 pandemic regulations in New York City required a novel workflow to sustain existing operations.While regulatory enforcement discretions offered faculty workspace flexibility, a substantial
Simulated alignments are alternatives to manually constructed multiple sequence alignments for evaluating performance of multiple sequence alignment tools.The importance of simulated sequences eyebrow is recognized because their true evolutionary history is known, which is very helpful for reconstructing accurate phylogenetic trees and alignments.H
Hydrogen cyanide (HCN) gas based fiber Bragg grating (FBG) interrogation is a promising approach in thermal cycling environment.However, the HCN spectrum suffers from strong noise and baseline wander induced by the interrogation system, which limits the measurement stability and reliability.In this paper, we propose an integrated method for spectra